Christina Applegate and Jamie-Lynn Sigler on Navigating MS

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Christina Applegate and Jamie-Lynn Sigler met in 2021 after Applegate was diagnosed with MS. Sigler, who was diagnosed in 2002, says Applegate ‘opened me up.’

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Christina Applegate, 52, tears up as she admits her MS has left her in constant and 'excruciating pain' - while revealing symptoms that first alerted her to debilitating condition she has been

Actresses Christina Applegate and Jamie-Lynn Sigler are opening up for the first time together about the health issue they both share: mu