How small proteins called chemokines could be the answer to getting cancer-busting CAR-T cells directly into solid tumours - Carina Biotech

Figure 1. CAR-T cells versus the solid tumor microenvironment (from Foeng et al 2022). ____________ It is now no secret that chimeric antigen receptor (CAR)-T cell therapy has produced remarkable […]

PDF) Mitochondrial metabolism sustains CD8 T cell migration for an efficient infiltration into solid tumors

CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity - ScienceDirect

IJMS February-2 2024 - Browse Articles

How chemokines organize the tumour microenvironment

Cancers, Free Full-Text

Chemokines, costimulatory molecules and fusion proteins for the immunotherapy of solid tumors

Surpassing CAR-T, CAR-M drives the solid tumor treatment forward - ACROBiosystems

Kathy Sharrard, Author at Carina Biotech

Gene modification strategies for next-generation CAR T cells against solid cancers, Journal of Hematology & Oncology

CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells - ScienceDirect

PDF) Mitochondrial metabolism sustains CD8 T cell migration for an efficient infiltration into solid tumors

CAR-based therapies: opportunities for immuno-medicine beyond cancer

Cancers, Free Full-Text

Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer - ScienceDirect

The exosomes derived from CAR-T cell efficiently target mesothelin and reduce triple-negative breast cancer growth - ScienceDirect