Bioengineering, Free Full-Text
$ 17.99 · 4.7 (189) · In stock
Extensive damage to skeletal muscle tissue due to volumetric muscle loss (VML) is beyond the inherent regenerative capacity of the body, and results in permanent functional debilitation. Current clinical treatments fail to fully restore native muscle function. Recently, cell-based therapies have emerged as a promising approach to promote skeletal muscle regeneration following injury and/or disease. Stem cell populations, such as muscle stem cells, mesenchymal stem cells and induced pluripotent stem cells (iPSCs), have shown a promising capacity for muscle differentiation. Support cells, such as endothelial cells, nerve cells or immune cells, play a pivotal role in providing paracrine signaling cues for myogenesis, along with modulating the processes of inflammation, angiogenesis and innervation. The efficacy of cell therapies relies on the provision of instructive microenvironmental cues and appropriate intercellular interactions. This review describes the recent developments of cell-based therapies for the treatment of VML, with a focus on preclinical testing and future trends in the field.
19 Interesting Facts About Biomedical Engineering
The Preclinical And Clinical Progress Of Cell Sheet, 41% OFF
Bioengineering, Free Full-Text
3 scenarios for how bioengineering could change our world in 10 years
Frontiers Bioengineering a Future Free of Marine Plastic Waste
Gel Printing with Vega Brennan, gel printing
Reasonably Priced Richness Abrazo Health using AI-powered EEG system for seizure detection, seizure monitor for adults
Bioengineering An Open Access Journal from MDPI
Biomedical Engineering Fundamentals
On a Robust, Sensitive Cell-Free Method for Pseudomonas Sensing